What are Sirtuins and How can Supplementation Help?

In the quest for optimal health and vitality, understanding the intricate workings of the body's cellular mechanisms is paramount. Among these, sirtuins play a pivotal role in regulating various processes that contribute to overall well-being. Sirtuins also have the potential to enhance energy levels to help you thrive.

However, sometimes our bodies can’t naturally produce enough of the things they need. This is where targeted supplementation like the Optima Max range from NADdirect can help to transform your wellness. In this blog, we explore what sirtuins do for the body and which products from the innovative Optima Max range can help.

Sirtuins 101

What Are Sirtuins?

Sirtuins are a class of proteins found in cells throughout the body, often referred to as longevity proteins due to their involvement in regulating cellular health and longevity. These proteins play a crucial role in numerous biological pathways, including metabolism, DNA repair, inflammation, and stress response. By modulating gene expression and influencing the activity of other proteins, sirtuins help maintain cellular homeostasis and promote resilience against various stressors, both internal and external.

What Do They Do?

One of the key functions of sirtuins is their ability to regulate energy metabolism. They govern the production and utilisation of energy within cells by orchestrating processes such as glucose metabolism, fatty acid oxidation, and mitochondrial function. By optimising these metabolic pathways, sirtuins ensure efficient energy production while minimising oxidative stress and metabolic dysfunction, thereby supporting overall vitality and health.

What Affects Sirtuin Activity?

However, the activity of sirtuins can be influenced by various factors, including lifestyle choices, environmental stressors, and ageing. Fortunately, emerging research suggests that certain wellness practices and dietary interventions can help activate sirtuins, unleashing their full potential to enhance energy levels and promote wellness.

Regular physical activity, for instance, boosts sirtuin activity, thereby improving metabolic health and increasing energy expenditure. Additionally, practices like intermittent fasting and calorie restriction activate sirtuins, stimulating cellular repair mechanisms and promoting longevity. Moreover, specific dietary compounds, such as resveratrol found in red grapes and blueberries, have been identified as sirtuin activators, further highlighting the potential of nutritional interventions in supporting cellular health.

Supplementation For Sirtuin Health

As mentioned above, there are a variety of ways to support sirtuin activity in your body. But, here at NADclinic we pride ourselves on finding solutions that allow you to be ‘Conscious without Compromise’. This means you can enjoy the lifestyle you love whilst reaping the benefits of the right vitamins and substances your body needs to thrive. 

Enhanced Optima Max

Containing a potent 250mg of the miracle molecule NAD+, this supplement gives you a total energy boost in every tablet. There is a direct link between optimum NAD+ levels and proper sirtuin activity, and both decrease with age. 

Pure Resveratrol

Resveratrol is a known key sirtuin activator. Naturally occurring in small quantities in foods like red grapes and blueberries. But, supplementation allows you to make this vital nutrient a consistent part of your diet. This supplement is our number 1 gold standard sirtuin activator. The capsules contain 500mg of pure resveratrol each. So, it is the ultimate way to ensure optimal sirtuin health without compromising on the food you enjoy.

To learn more about how the Optima Max range can help you take your wellness to the next level, check out our full supplement range on our website.